In vitro sensitivity and resistance of 46 Leptospira strains isolated from rats in the Philippines to 14 antimicrobial agents.

نویسندگان

  • Antara Chakraborty
  • Satoshi Miyahara
  • Sharon Y A M Villanueva
  • Nina G Gloriani
  • Shin-Ichi Yoshida
چکیده

The in vitro susceptibilities of 46 Leptospira isolates from rats to 14 antimicrobial agents were tested. All of the strains were found to be sensitive to ampicillin, cefotaxime, ciprofloxacin, norfloxacin, doxycycline, erythromycin, and streptomycin. In contrast, the tested isolates showed resistance to amphotericin B, 5-fluorouracil, fosfomycin, trimethoprim, sulfamethoxazole, neomycin, and vancomycin. These findings will help in selecting effective and ineffective antimicrobials for treatment of leptospirosis and for the development of new selective media, respectively.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 54 12  شماره 

صفحات  -

تاریخ انتشار 2010